The DAXXIFY® Difference
Discover what makes DAXXIFY® different: a first-of-its-kind peptide formulation with no human or animal by-products, backed by the largest clinical trial program of its kind.
An Entirely New Kind of Formulation
DAXXIFY® isn't a reformulated version of an existing treatment—it's a genuinely new approach. It's the first injectable frown-line treatment built around a peptide, rather than the human serum albumin used in traditional options.
That single formulation change has ripple effects across how the treatment performs, how fast it works, and how long it lasts.
Key Innovation Highlights:
- Proprietary cell-penetrating peptide stabilizer
- Formulated without human blood-derived proteins or serum albumin
- Contains no animal by-products for a cleaner formulation profile

How the Peptide Works
Think of the peptide as a delivery upgrade. It's positively charged, which helps it form a stronger bond with the target nerve cell, almost like a magnet drawing the active ingredient into place.
Targeted Efficient Delivery
It helps more of the active treatment reach its target efficiently, rather than being lost along the way during administration.
Extended Availability
It keeps the active ingredient available for longer at the nerve junction, which is a major reason results last as long as they do (up to 6 months).
And because the formulation doesn't depend on human blood-derived proteins or animal by-products, it's also a cleaner formulation profile for patients who care about what's actually being injected.
Largest Clinical Program
DAXXIFY® was evaluated in one of the largest clinical trial programs ever conducted for a frown-line treatment, spanning thousands of patients across a wide range of skin tones and types, with many participants receiving repeat treatments to confirm consistent, reliable results over time.
Made in the USA
DAXXIFY® is manufactured entirely in the United States, in California, adding a level of supply chain transparency and quality control that matters to a lot of our patients.
Recognized by Industry
DAXXIFY® has picked up national recognition, including Aesthetic & Skincare treatment awards from major beauty and wellness publications, for being a genuine step forward in the category rather than another me-too injectable.
